diff --git a/CHANGES.md b/CHANGES.md
index ce3b0adae583a63f114a4749e2ad000a7bfe23c9..14248686be5cc51ce18f4ed68d847a689fd10cb5 100644
--- a/CHANGES.md
+++ b/CHANGES.md
@@ -1,3 +1,9 @@
+Synapse 1.43.0 (2021-09-21)
+===========================
+
+No significant changes.
+
+
 Synapse 1.43.0rc2 (2021-09-17)
 ==============================
 
diff --git a/debian/changelog b/debian/changelog
index 7774cad55bec38fb72936839662c4a0daf38296c..4b07d0412875b91f09bbf89c25ae7d65edbce11b 100644
--- a/debian/changelog
+++ b/debian/changelog
@@ -1,3 +1,9 @@
+matrix-synapse-py3 (1.43.0) stable; urgency=medium
+
+  * New synapse release 1.43.0.
+
+ -- Synapse Packaging team <packages@matrix.org>  Tue, 21 Sep 2021 11:49:05 +0100
+
 matrix-synapse-py3 (1.43.0~rc2) stable; urgency=medium
 
   * New synapse release 1.43.0~rc2.
diff --git a/synapse/__init__.py b/synapse/__init__.py
index c9ef90ccaa5cecce14e25c943196f17272b12130..5f5cff1dfdcdf8c0ceeccc1051d1dca4250bbc31 100644
--- a/synapse/__init__.py
+++ b/synapse/__init__.py
@@ -47,7 +47,7 @@ try:
 except ImportError:
     pass
 
-__version__ = "1.43.0rc2"
+__version__ = "1.43.0"
 
 if bool(os.environ.get("SYNAPSE_TEST_PATCH_LOG_CONTEXTS", False)):
     # We import here so that we don't have to install a bunch of deps when