diff --git a/changelog.d/10712.feature b/changelog.d/10712.feature
new file mode 100644
index 0000000000000000000000000000000000000000..d04db6f26febf4b215f040a3c50d197c62189b52
--- /dev/null
+++ b/changelog.d/10712.feature
@@ -0,0 +1 @@
+Skip final GC at shutdown to improve restart performance.
diff --git a/synapse/app/_base.py b/synapse/app/_base.py
index 39e28aff9fb6ed5318c7f25be5b3c93e33e5f0df..6fc14930d1cdc4d49a920397418cd1972b0318d4 100644
--- a/synapse/app/_base.py
+++ b/synapse/app/_base.py
@@ -12,6 +12,7 @@
 # WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
 # See the License for the specific language governing permissions and
 # limitations under the License.
+import atexit
 import gc
 import logging
 import os
@@ -403,6 +404,12 @@ async def start(hs: "HomeServer"):
         gc.collect()
         gc.freeze()
 
+    # Speed up shutdowns by freezing all allocated objects. This moves everything
+    # into the permanent generation and excludes them from the final GC.
+    # Unfortunately only works on Python 3.7
+    if platform.python_implementation() == "CPython" and sys.version_info >= (3, 7):
+        atexit.register(gc.freeze)
+
 
 def setup_sentry(hs):
     """Enable sentry integration, if enabled in configuration